A significant number of Citrix NetScaler devices continue to pose serious security risks, with approximately 7,000 systems still vulnerable to two critical exploits that have been added to the Cybersecurity and Infrastructure Security Agency’s (CISA) Known Exploited Vulnerabilities (KEV) catalog.
The ongoing exposure highlights persistent challenges in enterprise patch management and cybersecurity hygiene.
Widespread Network Exposure Persists
Security researchers have identified 3,312 devices still susceptible to CVE-2025-5777 and 4,142 systems vulnerable to CVE-2025-6543, representing a substantial attack surface for malicious actors.
These NetScaler appliances, commonly deployed as application delivery controllers and load balancers in enterprise environments, serve as critical infrastructure components that often handle sensitive network traffic and provide access to internal resources.
The vulnerability landscape surrounding these devices is particularly concerning given their strategic position within network architectures.
NetScaler appliances typically sit at network perimeters, making them attractive targets for attackers seeking initial access to corporate environments.
When compromised, these systems can provide adversaries with privileged network access and the ability to intercept or manipulate critical business communications.
The inclusion of both vulnerabilities in CISA’s KEV catalog underscores the active exploitation risks these flaws present.

The KEV designation requires federal agencies to patch these vulnerabilities within specified timeframes and serves as a strong indicator for private sector organizations to prioritize remediation efforts.
This classification reflects evidence of real-world exploitation attempts and the potential for widespread compromise.
Organizations utilizing Citrix NetScaler infrastructure face immediate pressure to implement available security updates, as the KEV listing typically correlates with increased scanning and exploitation activities by threat actors.
The dual vulnerability exposure creates multiple attack vectors that adversaries can leverage depending on system configurations and defensive measures in place.
The Dutch National Cyber Security Centre (NCSC) has taken proactive steps by releasing updated guidance specifically addressing CVE-2025-6543 activity, indicating that international cybersecurity agencies are closely monitoring exploitation attempts.
This coordinated response suggests that the vulnerabilities may be experiencing active exploitation campaigns that have caught the attention of multiple national security organizations.
The Dutch NCSC’s involvement highlights the global nature of the threat, as NetScaler devices are deployed across international enterprise networks.
Their guidance likely provides specific indicators of compromise and recommended detection methodologies for organizations seeking to identify potential exploitation attempts.
The persistent exposure of thousands of vulnerable devices demonstrates critical gaps in organizational security processes.
IT administrators must immediately prioritize patching these systems and implement additional monitoring to detect potential compromise.
The combination of KEV classification and active international advisory coordination indicates that delayed remediation significantly increases organizational risk exposure.
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